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. 2019 Jan 9;12:4. doi: 10.1186/s13045-018-0691-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Analysis of the CAF levels in blood and bone marrow plasma samples of MM patients. No differences are evident in their concentration between peripheral blood and bone marrow samples. Significantly higher levels of CAFs are detected in blood and bone marrow samples of MM patients as compared with control subjects (p < 0.0001 for all cytokines)