Table 2.
Time-kill adevonin kinetics against K. oxytoca ATCC 13182 and S. aureus ATCC 80958. Control corresponds to bacteria suspensions incubated with NaCl 0.9%. Adevonin was incubated at MIC concentration and the respective treatments. The antibiotic chloramphenicol was used at 4 µg.mL−1. The results are showed as CFU/mL−1.
| Time (min) | K. oxytoca control | K. oxytoca + adevonin | K. oxytoca + antibiotic | S. aureus + adevonin | S. aureus control | S. aureus + antibiotic |
|---|---|---|---|---|---|---|
| 0 | >105 | >105 | >105 | >105 | >105 | >105 |
| 5 | >105 | >105 | >105 | >105 | >105 | >105 |
| 10 | >105 | 2 | >105 | >105 | >105 | >105 |
| 15 | >105 | 0 | >105 | >105 | >105 | >105 |
| 20 | >105 | 0 | >105 | 102 | >105 | >105 |
| 25 | >105 | 0 | >105 | 8 | >105 | 102 |
| 30 | >105 | 0 | >105 | 0 | >105 | 102 |
| 60 | >105 | 0 | 103 | 0 | >105 | 35 |
| 90 | >105 | 0 | 52 | 0 | >105 | 30 |
| 120 | >105 | 0 | 102 | 0 | >105 | 103 |