Ebselen influences the expression of apoptosis-related proteins. The effects of ebselen on C-Caspase-8, C-Caspase-3, Bax, Bcl-2 and C-PARP were analyzed by western blotting. The bar graphs indicate the quantification and statistical analysis of western blotting data. Data are expressed as the mean ± standard error of the mean. *P<0.05 and **P<0.01 vs. sham group; #P<0.05 vs. I/R group. I/R, ischemia/reperfusion; E, ebselen; C-, cleaved; Bcl-2, B-cell lymphoma 2; Bax, B-cell lymphoma 2-associated X protein; PARP, poly(ADP) ribose.