Table 1.
All patients | Initial set | Validation set | ||||
---|---|---|---|---|---|---|
Nb | % | Nb | % | Nb | % | |
Nb patients | 12,572 | 8381 | 4191 | |||
Age median (range) | 58 (18–101) | 58 (18–101) | 58 (18–100) | |||
< 60 | 7231 | 58 | 4857 | 58 | 2374 | 57 |
61–65 | 1810 | 14 | 1166 | 14 | 644 | 15 |
> 65 | 3525 | 28 | 2355 | 28 | 1170 | 28 |
Median tumor size | 14 | 14 | 14 | |||
< 10 | 4701 | 38 | 3136 | 38 | 1565 | 38 |
11 to 20 | 5053 | 41 | 3368 | 41 | 1685 | 41 |
> 20 | 2679 | 22 | 1784 | 22 | 895 | 22 |
No SN removed | ||||||
1 | 3268 | 31 | 2203 | 31 | 1065 | 31 |
2 | 3374 | 32 | 2231 | 31 | 1143 | 33 |
3 | 2034 | 19 | 1382 | 20 | 652 | 19 |
> 4 | 1886 | 18 | 1271 | 18 | 615 | 18 |
Tumor type | ||||||
Ductal | 9793 | 78 | 6522 | 78 | 3271 | 78 |
Lobular | 1645 | 13 | 1110 | 13 | 535 | 13 |
Mixt | 226 | 2 | 144 | 2 | 82 | 2 |
Others | 899 | 7 | 599 | 7 | 300 | 7 |
Grade | ||||||
1 | 4246 | 34 | 2891 | 35 | 1355 | 33 |
2 | 5756 | 46 | 3800 | 46 | 1956 | 47 |
3 | 2448 | 20 | 1611 | 19 | 837 | 20 |
LVI | ||||||
Negative | 8430 | 78 | 5661 | 78 | 2769 | 77 |
Positive | 2400 | 22 | 1595 | 22 | 805 | 23 |
Estrogen receptors | ||||||
negative | 1730 | 14 | 1146 | 14 | 584 | 14 |
positive | 10,828 | 86 | 7227 | 86 | 3601 | 86 |
Progesterone receptors | ||||||
negative | 3464 | 29 | 2281 | 29 | 1183 | 30 |
positive | 8522 | 71 | 5701 | 71 | 2821 | 70 |
Hormonal receptors | ||||||
negative | 1541 | 12 | 1020 | 12 | 521 | 12 |
positive | 11,013 | 88 | 7349 | 88 | 3664 | 88 |
Her2 status | ||||||
negative | 11,350 | 90 | 7570 | 90 | 3780 | 90 |
positive | 1222 | 10 | 811 | 10 | 411 | 10 |
Tumor sub types | ||||||
Luminal A | 8998 | 72 | 6026 | 72 | 2972 | 71 |
Luminal B Her2- | 1178 | 9 | 756 | 9 | 422 | 10 |
HR+ Her2+ | 766 | 6 | 521 | 6 | 245 | 6 |
HR- Her 2+ | 450 | 4 | 288 | 3 | 162 | 4 |
Triple Negative | 1091 | 9 | 732 | 9 | 359 | 9 |
pN final | ||||||
pN0(i-) | 8253 | 66 | 5507 | 66 | 2746 | 66 |
pN0(i+) | 355 | 3 | 233 | 3 | 122 | 3 |
pN1mi | 970 | 8 | 660 | 8 | 310 | 7 |
Macro | 2994 | 24 | 1981 | 24 | 1013 | 24 |
Clinical size | ||||||
T0 | 2764 | 23 | 1831 | 23 | 933 | 23 |
T1 | 6784 | 57 | 4544 | 57 | 2246 | 56 |
T2 | 2115 | 18 | 1383 | 17 | 732 | 18 |
> T3 | 283 | 2 | 187 | 2 | 96 | 2 |