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. 2018 Dec 3;17(2):1330–1336. doi: 10.3892/etm.2018.7042

Figure 4.

Figure 4.

AKT1 overexpression partially reverses miRNA-490-3p-induced apoptosis. The effect of AKT1 on (A) SNU-1 and (B) N87 cell growth was analyzed by cell counting kit-8 assay following miRNA-490-3p overexpression. The effect of AKT1 on the rate of apoptosis in (C) SNU-1 and (D) N87, following overexpression of miRNA-490-3p. *P<0.05 vs. mimics-NC, #P<0.05 vs. mimics-NC+pcDNA-NC. AKT1, protein kinase B; GC, gastric cancer; SNU-1 and N87, GC cell lines; NC, negative control; mimics-NC, GC cell line (SNU-1 or N87) transfected with miRNA-NC inhibitor; mi-mimics + pcDNA-NC, co-transfection with miRNA-490-3p mimic and negative control in GC cell lines; mi-mimics + pcDNA-AKT1, co-transfection with miRNA-490-3p mimic and AKT1 in GC cell lines.