Figure 3.

Everolimus exerted inhibition on MCF-7-P cells migration and epithelial-mesenchymal transition (EMT) process. (A) Cell migration ability was measured in MCF-7 and MCF-7-P cells. (B, C) Expression of EMT markers (E-cadherin and vimentin) was detected in MCF-7 and MCF-7-P cells. (D) MCF-7-P cells were treated with different concentrations of everolimus, and followed by examining the migration ability via Transwell migration assay. (E, F) EMT markers (E-cadherin and vimentin) expression was determined in cells depicted in (D). Data were presented as mean ± standard deviation; * P<0.05, ** P<0.01 versus control.