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. 2018 May 26;11(1):74–79. doi: 10.1136/neurintsurg-2018-013935

Table 1.

Comparison of neointimal ratio, stent-coverage ratio, and thrombus formation among stents

Flex Shield Solitaire P value
Flex vs
Shield
P value
Shield vs
Solitaire
P value
Flex vs
Solitaire
Neointimal ratio on day 21
 SAPT 0.21±0.16* 0.22±0.11* 0.044±0.12 NS <0.001 <0.001
 DAPT 0.087±0.10 0.095±0.063 0.023±0.012 NS <0.001 <0.001
 Total 0.12±0.13 0.13±0.098 0.032±0.081 NS <0.05 <0.05
Stent-coverage ratio on day 7
 SAPT 0.82±0.24* 0.79±0.24* 0.78±0.22 NS NS NS
 DAPT 0.32±0.28 0.59±0.36 0.81±0.22 <0.001 <0.001 <0.001
Stent-coverage ratio on day 14
 SAPT 0.93±0.096 0.92±0.13 0.81±0.28 NS NS NS
 DAPT 0.92±0.093 0.93±0.13 0.90±0.16 <0.001 NS 0.031
Stent-coverage ratio on day 21
 SAPT 0.96±0.10* 0.98±0.059* 0.85±0.27 NS 0.011 NS
 DAPT 0.88±0.15 0.93±0.12 0.86±0.18 0.002 NS NS
%Thrombus formation on day 7
 SAPT 100±0.00* 36.36±48.38* 43.08±49.90 <0.001 NS <0.001
 DAPT 9.42±29.32 9.40±29.28 33.33±47.35 ns <0.001 <0.001
 Total 39.02±48.90 19.41±39.63 36.93±48.40 <0.001 <0.001 NS

*P<0.001 compared with DAPT.

DAPT, dual antiplatelet therapy; Flex, Pipeline Flex embolization device; SAPT, single antiplatelet therapy; Shield, Pipeline Flex embolization with Shield technology.