Table 1.
Flex | Shield | Solitaire | P value Flex vs Shield |
P value Shield vs Solitaire |
P value Flex vs Solitaire |
|
Neointimal ratio on day 21 | ||||||
SAPT | 0.21±0.16* | 0.22±0.11* | 0.044±0.12 | NS | <0.001 | <0.001 |
DAPT | 0.087±0.10 | 0.095±0.063 | 0.023±0.012 | NS | <0.001 | <0.001 |
Total | 0.12±0.13 | 0.13±0.098 | 0.032±0.081 | NS | <0.05 | <0.05 |
Stent-coverage ratio on day 7 | ||||||
SAPT | 0.82±0.24* | 0.79±0.24* | 0.78±0.22 | NS | NS | NS |
DAPT | 0.32±0.28 | 0.59±0.36 | 0.81±0.22 | <0.001 | <0.001 | <0.001 |
Stent-coverage ratio on day 14 | ||||||
SAPT | 0.93±0.096 | 0.92±0.13 | 0.81±0.28 | NS | NS | NS |
DAPT | 0.92±0.093 | 0.93±0.13 | 0.90±0.16 | <0.001 | NS | 0.031 |
Stent-coverage ratio on day 21 | ||||||
SAPT | 0.96±0.10* | 0.98±0.059* | 0.85±0.27 | NS | 0.011 | NS |
DAPT | 0.88±0.15 | 0.93±0.12 | 0.86±0.18 | 0.002 | NS | NS |
%Thrombus formation on day 7 | ||||||
SAPT | 100±0.00* | 36.36±48.38* | 43.08±49.90 | <0.001 | NS | <0.001 |
DAPT | 9.42±29.32 | 9.40±29.28 | 33.33±47.35 | ns | <0.001 | <0.001 |
Total | 39.02±48.90 | 19.41±39.63 | 36.93±48.40 | <0.001 | <0.001 | NS |
*P<0.001 compared with DAPT.
DAPT, dual antiplatelet therapy; Flex, Pipeline Flex embolization device; SAPT, single antiplatelet therapy; Shield, Pipeline Flex embolization with Shield technology.