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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Oct 25;143(1):245–257.e6. doi: 10.1016/j.jaci.2018.10.018

FIG 2.

FIG 2.

Preferential expression of RORγt by surviving Gimap5sph/sph CD4+ T cells upon TCR stimulation. (A) Proliferation of WT and Gimap5sph/sph CD4+ T cells after 3 days stimulation with αCD3 (1 μg/ml) + αCD28 (2 μg/ml). (B) Survival CD4+ T cells after 3d stimulation. (C) Expression of RORγt in live CD4+ T cells after 3d stimulation with αCD3/αCD28. Plots depict live cells (C), while bar graphs (B) represent mean values ± SD (n=4). All experiments were performed at least three times. Statistical significance is determined by Student’s two-tailed test. ****P<0.0001