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. 2019 Jan 7;34(1):420–428. doi: 10.1080/14756366.2018.1484734

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Interaction between miR-25–3p and COL1A2 in PC cells. (A) COL1A2 expression was detected by qRT-PCR in four groups, including PANC-1 and SW1990 cells were transfected with pcDNA 3.1-neo vectors (NC), pcDNA 3.1-COL1A2, miR-25–3p mimics and miR-25–3p mimics + pcDNA 3.1-COL1A2 (mix). (B-C) MTT assay was applied to detect the proliferation of PANC-1 and SW1990 cells in four groups. (D-E) Transwell assay was used for the detection of migration and invasion in PANC-1 and SW1990 cells. *p < .05 indicated significant differences compared with NC groups or mix groups. *, p < .05; **, p < .01.