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. 2019 Jan 3;34(1):361–374. doi: 10.1080/14756366.2018.1553167

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 13. — (A) Cartoon/surface representations of the interaction between 17 with the PIF-pocket of PDK1 (pale yellow; PDB ID: 4XX9). (B) Comparison of the helix αB and helix αC of PDK1-17 complex, PDK1-13 complex (slate) and PDK1-4 complex (salmon). (C) Comparison of the ATP of PDK1-17 complex, PDK1-13 complex, and PDK1-4 complex.