Table 4.
Clinical and laboratory factors affecting eGFR
| Variables | Correlation | P value |
|---|---|---|
|
| ||
| Clinical parameters | ||
| Age (years) | −0.353 | 0.000* |
| Sex | −0.109 | 0.081 |
| Age at diagnosis of SCA (mon) | −0.085 | 0.436 |
| Weight (kg) | −0.146 | 0.027* |
| SBP (mmHg) | −0.148 | 0.021* |
| DBP (mmHg) | −0.213 | 0.001* |
| VOC/yr | 0.012 | 0.862 |
| Total blood transfusion | −0.276 | 0.000* |
|
| ||
| Haematological parameters | ||
| PCV (%) | 0.371 | 0.000* |
| WBC (x 109/L) | 0.006 | 0.931 |
| Platelets (x 109/L) | 0.146 | 0.131 |
|
| ||
| Biochemical indices | ||
| Urea (mmol/l) | 0.527 | 0.000* |
| Creatinine (μmol/l) | 0.625 | 0.000* |
| Uric acid (mmol/l) | −0.419 | 0.000* |
*
Significant result. SBP: Systolic blood pressure, DBP: Diastolic blood pressure, PCV: packed cell volume, WBC: white blood cell count.