Table 2. Comparison of systemic sclerosis patients with interstitial lung disease and those not.
| Clinical features | SSc with ILD (n=43) | SSc without ILD (n=65) | |||||
| n | % | Mean±SD | n | % | Mean±SD | p | |
| Age (year) | 51.34±14.55 | 49.23±13.51 | 0,49 | ||||
| Gender | 0,92 | ||||||
| Female | 38 | 57 | |||||
| Male | 5 | 8 | |||||
| Duration (year) | 6.72±5.02 | 4.28±3.50 | 0.012* | ||||
| Subtype | 0,33 | ||||||
| Diffuse | 22 | 27 | |||||
| Limited | 21 | 38 | |||||
| Antinuclear antibody (+) | 42 | 97,7 | 62 | 95,4 | 0,54 | ||
| Anti-scleroderma 70 (+) | 27 | 62,8 | 10 | 15,4 | <0.001 | ||
| Anti-centromere (+) | 4 | 9,3 | 33 | 50,8 | <0.001 | ||
| White blood cells (µL) | 7650.9±2656.2 | 6469.0±1858.1 | 0.022* | ||||
| Platelet (¥103/µL) | 282.1±81.7 | 241.3±66.5 | 0.007* | ||||
| Erythrocyte sedimentation rate (mm/h) | 39.4±27.3 | 26.5±22.0 | 0.008* | ||||
| C-reactive protein (mg/dL) | 1.2±3.1 | 0.3±1.4 | 0,1 | ||||
| Raynaud’s phenomenon | 42 | 97,7 | 64 | 98,5 | 0,77 | ||
| Sclerodactyly | 38 | 88,4 | 59 | 90,8 | 0,69 | ||
| Skin rash | 11 | 25,6 | 17 | 26,2 | 0,95 | ||
| Digital ulcer | 15 | 34,9 | 12 | 17,9 | 0,06 | ||
| Arthritis | 23 | 53,5 | 34 | 52,3 | 0,91 | ||
| Gastrointestinal involvement | 21 | 48,8 | 23 | 35,4 | 0,17 | ||
| Pulmonary hypertension | 11 | 25,6 | 2 | 3,1 | <0.001* | ||
| SSc: Systemic sclerosis; ILD: Interstitial lung disease; SD: Standard deviation; * p-value <0.05. | |||||||