Table 2. Efficacy of mizoribine and methotrexate.
Mizoribine (n=14) | Methotrexate (n=10) | ||||
n | Mean±SE | n | Mean±SE | p | |
Prednisone dose | |||||
0-48 week (mg) | 1907±241 | 2272±396 | 0,41 | ||
0-24 week (mg) | 1288±163 | 1311±207 | 0,93 | ||
24-48 week (mg) | 619±92 | 962±232 | 0,14 | ||
At baseline (mg/day) | 12.1±1.8 | 11.4±1.8 | 0,70 | ||
At 48 week (mg/day) | 2.6±0.5 | 4.7±1.1 | 0,07 | ||
≤5 mg at 48 week | 13 | 6 | 0,12 | ||
Patients who ceased prednisone | 3 | 1 | 0,62 | ||
Flare-ups | 5 | 2 | 0,65 | ||
SE: Standard error. |