Table 1.

Definition of terms used in this study

Terms	Definitions
Deep SSI	Clinical, biological and radiological signs of SSI associated with at least 2 deep samples (subfascial) of bone, tissue or fluids surrounding the material, positive for the same pathogen(s)
Biological inflammatory response	CRP > 10mg/L and/or WBC > 10G/L
Early onset infection	SSI occurring within the 30 days after index surgery
Delayed infection	SSI occurring between 1 and 3 months after index surgery
Late onset infection	SSI occurring after 3 months after index surgery
Persistence	Need for a new surgical revision because of persistent or increasing signs of SSI beyond 7 days after the beginning of DAIR protocol but before the end of antibiotic treatment, with intraoperative samples positive for the same pathogen (negative cultures do not exclude this diagnosis)
Relapse	Reappearance of signs of infection with samples growing the same pathogen after the end of antibiotic treatment within 1 year after initial surgery
Treatment failure	Persistence or relapse of SSI
New infection	New SSI with a pathogen different from the one responsible for the initial infection within 1 year of follow-up
Patient cured	Absence of relapse after 1 year (no surgical revision, no clinical sign of infection, CRP <10 mg/L and no radiological sign of infection), off antibiotic therapy

SSI: Surgical site infection; CRP: C-reactive protein; WBC: White Blood Cells; DAIR: debridement-irrigation, antibiotic therapy and implant retention.