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. Author manuscript; available in PMC: 2019 Jan 10.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2777–2778. doi: 10.1161/ATVBAHA.111.237610

Figure 1.

Figure 1.

Demonstrates the Calcific Aortic Valve Disease: Cellular Origins of Valves Calcification and the mechanisms of osteogensis in these cell types. Panel A: The potential cellular phenotypes for mesenchymal derived cells, Panel B: The two different cell origins for valve calcification: the COP cell and the native interstitial cell both contributing to the hypothesis of osteogenesis in calcific aortic valve disease.