Fig. 7.

a Interaction profile of ZINC01721693–FabI complex in a wireframe model to reveal the residues involved in stabilization of the complex. Five hydrogen bonds represented by the blue dotted lines are responsible for the stabilization of the complex. b 2-D plot of interactions between ZINC01721693 and active site residues of FabI. Alanine, tyrosine, and methionine residues of the active site are involved in hydrogen bond formation with the ligand