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. 2019 Jan 4;12:498. doi: 10.3389/fncel.2018.00498

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Copyright © 2019 Xu, Xing, Huang, Zhou, Liu, Cui, Cheng, Wang, Zhou, Yang, Yang, Zhang, Zang, Ma and Guan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HDAC1 silence enhanced the engraftment of hUC-MSCs in the hippocampus of traumatic brain injury (TBI) mice. (A) Overview of experimental design and timeline for experiment. (B) Representative immunofluorescent images. (C) Quantification analysis of MAB1281⁺ (green) cells in the dentate gyrus of hippocampus, Scale bar = 200 μm. (D) Polymerase chain reaction (PCR) results of the human-specific DNA in the hippocampus of TBI mouse. Data were from three mice of each group and three slides of each mouse. Data are presented as mean ± SEM. *p < 0.05 vs. Vehicle, ^#p < 0.05 vs. MSCs.