Table 2.
Summary of seed-based brain functional connectivity results for neonates born to normal or high BMI mothers (see Supplement A for abbreviations of the AAL regions).
| Seed |
Cluster |
n-BMI (N = 23) |
h-BMI (N = 15) |
n-BMI vs. h-BMI |
BFM % |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| funPar # | AAL | AAL | # Vox | CM RL | CM AP | CM IS | μ | SE | μ | SE | t | p | r | p |
| 1 | PreCG-L | SMG-L | 2 | 39.5 | 23.0 | 23.5 | -0.10 | 0.06 | 0.30 | 0.07 | -4.26 | 0.0001 | 0.51 | 0.0009 |
| 14 | SFGdor-L | REC-L | 11 | 1.0 | -26.2 | -12.0 | -0.18 | 0.07 | 0.34 | 0.09 | -4.79 | 0.0000 | 0.59 | 0.0001 |
| 41 | ORBmid-L | MGF-L | 29 | 24.0 | -23.6 | 18.2 | -0.09 | 0.07 | 0.45 | 0.11 | -4.39 | 0.0001 | 0.39 | 0.0165 |
| 41 | ORBmid-L | MGF-L | 28 | 26.4 | -7.0 | 31.4 | -0.14 | 0.07 | 0.37 | 0.09 | -4.46 | 0.0001 | 0.45 | 0.0051 |
| 42 | ORBmid-R | MTG-L | 26 | 34.0 | 24.0 | -3.6 | -0.19 | 0.07 | 0.35 | 0.09 | -4.74 | 0.0000 | 0.54 | 0.0005 |
| 66 | SFGmed-L | PoCG-L | 6 | 40.5 | 5.5 | 19.0 | -0.29 | 0.06 | 0.17 | 0.07 | -5.29 | 0.0000 | 0.55 | 0.0004 |
| 72 | REC-L | MGF-L | 47 | 13.7 | -0.6 | 36.1 | -0.23 | 0.06 | 0.33 | 0.09 | -5.72 | 0.0000 | 0.63 | 0.0000 |
| 106 | PHG-R | SPG-R | 24 | -15.6 | 56.6 | 29.1 | -0.14 | 0.07 | 0.34 | 0.07 | -4.58 | 0.0001 | 0.60 | 0.0001 |
| 128 | MOG-R | FFG-R | 28 | -16.7 | 40.5 | -6.9 | -0.11 | 0.05 | 0.45 | 0.09 | -5.85 | 0.0000 | 0.52 | 0.0008 |
| 129 | MOG-R | LING-R | 15 | -15.3 | 40.9 | -5.9 | 0.00 | 0.05 | 0.54 | 0.09 | -5.49 | 0.0000 | 0.52 | 0.0007 |
| 139 | FFG-R | SOG-R | 54 | -16.2 | 58.0 | 20.0 | -0.01 | 0.05 | 0.49 | 0.10 | -5.14 | 0.0000 | 0.43 | 0.0070 |
| 146 | PoCG-R | PreCG-R | 2 | -25.0 | 15.5 | 38.5 | 0.70 | 0.08 | 1.33 | 0.10 | -4.82 | 0.0000 | 0.56 | 0.0002 |
| 174 | CAU-R | ORBinf-R | 5 | -10.3 | -10.3 | -9.5 | 0.25 | 0.06 | -0.29 | 0.09 | 5.42 | 0.0000 | -0.66 | 0.0000 |
| 192 | STG-R | PUT-R | 6 | -17.5 | 11.0 | 5.5 | -0.20 | 0.06 | 0.22 | 0.08 | -4.13 | 0.0002 | 0.41 | 0.0113 |
| 207 | TPOmid-L | MCG-L | 43 | -0.6 | 32.4 | 27.5 | 0.31 | 0.07 | -0.21 | 0.09 | 4.45 | 0.0001 | -0.46 | 0.0035 |
| 207 | TPOmid-L | SOG-L | 4 | 17.0 | 47.0 | 26.5 | 0.29 | 0.07 | -0.20 | 0.11 | 3.91 | 0.0004 | -0.45 | 0.0043 |
| 212 | ITG-L | LING-R | 14 | -13.0 | 59.6 | -6.9 | -0.33 | 0.08 | 0.15 | 0.08 | -4.22 | 0.0002 | 0.38 | 0.0179 |
Bold values indicate significance at P < 0.0002 (Bonferroni corrected; 0.05/223) funPar #, the sub-region number of each detected seed in our reference neonatal functional atlas; # Vox, number of voxels within the detected clusters; CM RL/AP/IS, MNI coordinates of the detected clusters in right-left, anterior-posterior, inferior-superior directions; n-BMI, normal body-mass-index group; h-BMI, high BMI group. BFM, maternal body-fat-mass percentage; μ, mean; SE, standard deviation; t, t-value; p-p value. r, Pearson correlation value.