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. 2019 Jan 4;9:1105. doi: 10.3389/fneur.2018.01105

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Copyright © 2019 Ding, Triggs, Kamath and Patten.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Short intracortical inhibition (SICI) in the IH in stroke survivors and healthy controls. Data presented are group mean ±SEM. ^* indicates significant difference (P < 0.05). During grip and B and B, SICI was significantly reduced in cortical stroke compared with healthy controls (P's = 0.03 and 0.012, respectively). Across tasks, SICI in cortical stroke was significantly reduced during grip and B and B compared with rest (P's = 0.04 and 0.017, respectively). Of note, background EMG activity, S2 MEP size, and MEP/EMG were not significantly different among groups during either grip or B and B, reducing likelihood that differences in motor excitability contribute to group-differences in SICI. IH, ipsilesional hemisphere; B and B, box and blocks task; MEP, motor-evoked potential. MEP/EMG refers to the ratio of S2 (unconditioned) MEP size to mean prestimulus EMG activity.