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. 2019 Jan 4;8:655. doi: 10.3389/fonc.2018.00655

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Copyright © 2019 Yu, Tang, Lin, Yao and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DGKZ expression in osteosarcoma samples and cells. (A–C) Representative images of osteosarcoma tissue with strong staining (brown) of DGKZ (Red circle represented characteristic positive position). (D) Osteosarcoma with negative DGKZ staining (Red circle represented characteristic negative position). (E) Normal bone tissue with negative DGKZ staining (Red circle represented characteristic negative position). (F) DGKZ expression is correlated with reduced progression-free survival in osteosarcoma patients. (G) DGKZ expression is correlated with reduced overall survival in osteosarcoma patients. (H) qPCR analysis of DGKZ expression in different osteosarcoma cell lines and human normal osteoblasts hFOB1.19.