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. 2018 Dec;30(6):677–678. doi: 10.21147/j.issn.1000-9604.2018.06.12

1.

Clinical studies of BRAF inhibition therapy for recurrent ameloblastoma

Author Gender Age (year) Metastasis Drug Dose Result
Kaye et al. Male 40 (+) Dabrafenib 150 mg, twice daily Notable tumor reduction on
recurrent and metastatic sites
Trametinib 2 mg, once daily
Faden et al. Female 83 (–) Dabrafenib 75 mg, twice daily Notable tumor reduction on recurrent site