1.
Baseline patient characteristics (N=20)
| Characteristics | n (%) |
| ECOG, Eastern Cooperative Oncology Group; *, Previous therapies included endocrine therapies and chemotherapies used in the adjuvant setting or to treat advanced disease. | |
| Age [median (range)] (year) | 56 (42, 75) |
| ECOG performance status | |
| 0 | 13 (65) |
| 1 | 7 (35) |
| Disease stage at study entry | |
| III | 1 (5) |
| IV | 19 (95) |
| Measurable disease | 14 (70) |
| Metastatic sites | |
| Visceral | 7 (35) |
| Liver | 3 (15) |
| Lung | 5 (25) |
| Liver and lung | 1 (5) |
| Bone only | 6 (30) |
| No. of previous therapies* | |
| 1 | 0 (0) |
| 2 | 5 (25) |
| ≥3 | 15 (75) |
| Prior therapies for metastatic disease | |
| Endocrine therapy | 11 (55) |
| Chemotherapy | 11 (55) |