S1.

Samples material in GSE49355 and GSE623

Samples	Normal_colon	Primary_tumor	Liver_metastasis
016_MV	Yes	Yes	Yes
003_JCP	No	No	Yes
005_JME	No	No	Yes
022_JB	Yes	Yes	No
026_SA	Yes	No	No
044_MB	Yes	Yes	Yes
045_JC	No	Yes	No
050_NC1B	No	No	Yes
056_MC	No	Yes	Yes
059_MT	Yes	Yes	Yes
061_CM	Yes	Yes	No
073_PD	Yes	Yes	Yes
094_AM	No	Yes	Yes
089_NC	Yes	No	Yes
109_JC	No	No	Yes
115_CB	Yes	Yes	Yes
119_PM	Yes	Yes	No
130_YL	No	Yes	No
149_JGI	Yes	Yes	Yes
179_AB	No	No	Yes
189_JR	Yes	Yes	No
196_TD	Yes	Yes	Yes
213_RG	Yes	Yes	Yes
222_PEC	Yes	Yes	Yes
227_SS	Yes	Yes	No
234_YC	Yes	No	No
223_GB	Yes	Yes	Yes
244_FP	No	Yes	Yes