Table 1.
Day | Protocol | n | Body weight (g) | Heart weight (mg) | HW/BW (mg/g) | DF (g) | Df/dt max (g/min) |
---|---|---|---|---|---|---|---|
1 | Controls | 12 | 6.67 ± 0.23 | 34.22 ± 1.33 | 5.15 ± 0.15 | 1.45 ± 0.11 | 35.25 ± 2.50 |
5-HD | 15 | 6.78 ± 0.22 | 33.05 ± 1.82 | 4.84 ± 0.16 | 1.40 ± 0.12 | 37.51 ± 4.47 | |
IPoC 5 × 10 s | 9 | 6.07 ± 0.30 | 24.96 ± 0.70 | 4.10 ± 0.08 | 1.29 ± 0.07 | 32.63 ± 1.24 | |
Nitrates/3-NT | 10 | 6.08 ± 0.28 | 26.40 ± 1.91 | 4.31 ± 0.14 | - | - | |
4 | Controls | 9 | 9.16 ± 0.46 | 42.92 ± 2.01 | 4.73 ± 0.20 | 2.08 ± 0.13 | 48.48 ± 2.01 |
5-HD | 8 | 8.98 ± 0.56 | 45.76 ± 2.85 | 5.14 ± 0.23 | 2.28 ± 0.21 | 58.85 ± 5.37 | |
IPoC 5 × 10 s | 8 | 10.55 ± 0.28 | 54.11 ± 3.20 | 5.15 ± 0.18 | 1.97 ± 0.15 | 51.92 ± 3.43 | |
7 | Controls | 8 | 15.50 ± 0.81 | 72.26 ± 2.81 | 4.70 ± 0.10 | 3.08 ± 0.22 | 78.96 ± 4.70 |
5-HD | 6 | 17.77 ± 0.58 | 81.12 ± 2.15 | 4.58 ± 0.16 | 2.99 ± 0.29 | 71.44 ± 4.28 | |
IPoC 5 × 10 s | 8 | 15.16 ± 0.36 | 71.35 ± 2.91 | 4.72 ± 0.21 | 2.99 ± 0.16 | 74.63 ± 3.41 | |
10 | Controls | 8 | 20.01 ± 1.04 | 98.55 ± 4.02 | 4.99 ± 0.31 | 3.54 ± 0.23 | 80.96 ± 7.62 |
5-HD | 12 | 20.28 ± 0.64 | 92.76 ± 2.98 | 4.62 ± 0.19 | 3.59 ± 0.24 | 83.44 ± 5.41 | |
IPoC 5 × 10 s | 10 | 18.81 ± 0.50 | 93.3 ± 2.53 | 4.97 ± 0.13 | 4.43 ± 0.30 | 100.30 ± 8.68 | |
IPoC 5 × 10 s + 5-HD | 9 | 18.92 ± 0.37 | 86.77 ± 2.08 | 4.56 ± 0.13 | 5.22 ± 0.26 | 129.52 ± 5.46 |
HW/BW heart weight-to-body weight ratio, DF developed force, Df/dt max the most force rising ratio, SEM standard error of mean