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. 2018 Dec 10;33(1):61–79. doi: 10.1007/s40263-018-0586-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Participant disposition. AE adverse event, BID twice daily, PR prolonged-release. ^a1 patient randomized to PR-fampridine withdrew from the study before dosing (reason: consent withdrawn). ^bPatients who completed the 24-week double-blind treatment period and 2-week off-treatment follow-up visit calculated as follows: 317 − 51 = 266. A total of 271 participants completed the 24-week treatment period (Weeks 0–24). ^cPatients who completed the 24-week double-blind treatment period and 2-week off-treatment follow-up visit calculated as follows: 319 − 65 = 254. A total of 258 participants completed the 24-week treatment period (Weeks 0–24)