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. 2019 Jan 10;10(1):31. doi: 10.1038/s41419-018-1241-2

Fig. 7. Schematic diagram summarizes the mechanism of resistin-boosted tumor angiogenesis in chondrosarcoma microenvironment.

Fig. 7

Resistin promotes VEGF-A production by downregulating miR-16-5p through PI3K/Akt-dependent pathway in human chondrosarcoma cells, and subsequently induces EPCs angiogenesis