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. 2019 Jan 10;10:105. doi: 10.1038/s41467-018-08040-w

Fig. 1.

Fig. 1

Efficacy of the PE cocktail in guinea pigs against EBOV and SUDV. a Survival, b health score, and c weight change in animals challenged with guinea pig-adapted EBOV (GPA-EBOV) and d day 7 viremia data, determined by RT-qPCR. Control group (n = 4) was given PBS while treatment groups (n = 6) received antibodies on day 3 postinfection. e Survival, f health score, g weight change, and h viremia by plaque assay (individual animals and mean ± SD) from animals (n = 6) challenged with guinea pig-adapted SUDV (GPA-SUDV) and treated 3 days postinfection or control animals given PBS (n = 6), LOD limit of detection. i Survival, j health score, and k weight change in animals (n = 6) treated 4 days postinfection with guinea pig-adapted SUDV (GPA-SUDV) or control animals (n = 6) given PBS. CHO (green) or 293T (blue) represent the cell line in which antibodies were produced. Error bars represent the mean value of the six animals in each group ± standard deviation (SD). Statistical analysis of survival was performed by log-rank test