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. 2018 Sep 8;151(1):5–20. doi: 10.1007/s00418-018-1719-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — qRT-PCR evaluation of total mRNA levels of colon (a–d) and ileum (e–h) from healthy and diseased mice. While CB₁ (a) and CB₂ (c) gene expression are not significantly altered in mice after DSS treatment, GPR55 (b) and MGL (d) gene expression are significantly reduced in DSS-induced colitis. In LPS-induced systemic inflammation, CB₁, CB₂ and GPR55 mRNA levels do not differ from healthy tissue (e–g). In contrast, MGL mRNA levels are reduced in comparison to healthy animals (h)