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. 2018 Jul 26;6(4):377–384. doi: 10.14218/JCTH.2018.00004

Table 2. Multivariate Cox proportional hazard model for predictors of death for Child-Pugh A patients.

Variable β HR 95% CI P
Sex, M/F −0.192 0.825 0.588, 1.157 0.265
Age, <60/≥60 years 0.058 1.060 0.779, 1.441 0.712
Tumor size, <5/≥5 cm 0.473 1.605 1.181, 2.181 0.003
BCLC, A/B 0.365 1.441 1.066, 1.947 0.017
AFP, <400/≥400 ng/μL 0.312 1.366 1.065, 1.752 0.014
ALT, ≤40/>40 U/L −0.207 0.813 0.616, 1.072 0.142
AST, ≤35/>35 U/L 0.407 1.502 1.103, 2.046 0.010
ALP, ≤150/>150 U/L 0.247 1.280 0.943, 1.738 0.113
GGT, ≤50/>50 U/L 0.350 1.419 1.032, 1.950 0.031
TBIL, ≤17.1/>17.1 μmol/L 0.011 1.011 0.776, 1.319 0.933
Platelet count, <100/100–300/>300 × 109/L −0.319 0.771 0.566, 0.933 0.012
PT, <12/12–14/>14 s 0.082 1.086 0.795, 1.482 0.604
Alb, <34/34–48/>48 g/L −0.246 0.782 0.501, 1.218 0.277
PA, male <120/120–190/>190 mg/L, female <110/110–170/>170 mg/L −0.313 0.731 0.606, 0.883 0.001

Abbreviations: Alb, albumin; AFP, alpha fetoprotein; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate transaminase; BCLC, Barcelona Clinic Liver Cancer; CI, confidence interval; GGT, gamma-glutamyl transferase; HR, hazard ratio; PA, prealbumin; PT, prothrombin time; TBIL, total bilirubin.