Table 4. Summary of the side effects of different genotype groups.
SNPs | Genotype | Patients (n) | Nausea (%) | Vomiting (%) | Respiratory depression (%) | Pruritus (%) |
---|---|---|---|---|---|---|
OPRM1 rs1799971 | AA | 115 | 4 (3.48%) | 3 (2.61%) | 2 (1.74%) | 1 (0.87%) |
AG | 78 | 2 (2.56%) | 1 (1.28%) | 1 (1.28%) | 1 (1.28%) | |
GG | 32 | 1 (3.13%) | 0 (0) | 0 (0) | 0 (0) | |
OPRM1 rs563649 | AA | 104 | 3 (2.88%) | 3 (2.88%) | 2 (1.92%) | 2 (1.92%) |
AG | 78 | 2 (2.56%) | 1 (1.28%) | 0 (0) | 0 (0) | |
GG | 43 | 2 (4.56%) | 0 (0) | 1 (2.33%) | 0 (0) | |
OPRM1 rs1323040 | CC | 124 | 5 (4.03%) | 4 (3.23%) | 3 (2.42%) | 2 (1.61%) |
CT | 79 | 3 (3.80%) | 0 (0) | 0 (0) | 0 (0) | |
TT | 22 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
ABCB1 rs2032582 | GG | 109 | 4 (3.67%) | 4 (3.67%) | 2 (1.8%) | 1 (0.92%) |
GT | 85 | 3 (3.53%) | 0 (0) | 1 (1.18%) | 0 (0) | |
TT | 31 | 0 (0) | 0 (0) | 0 (0) | 1 (3.23%) | |
ABCB1 rs1045642 | CC | 120 | 4 (3.33%) | 3 (2.50%) | 3 (2.50%) | 2 (1.67%) |
CT | 58 | 2 (3.45%) | 0 (0) | 0 (0) | 0 (0) | |
TT | 47 | 1 (2.13%) | 1 (2.13%) | 0 (0) | 0 (0) | |
ABCB1 rs1128503 | CC | 131 | 5 (3.82%) | 4 (3.05%) | 2 (1.53%) | 1 (0.76%) |
CT | 63 | 2 (3.17%) | 0 (0) | 1 (1.59%) | 1 (1.59%) | |
TT | 31 | 0 (0) | 0 (0) | 0 (0) | 0 (0) |