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. 2019 Jan 3;39(1):BSR20181211. doi: 10.1042/BSR20181211

Table 4. Summary of the side effects of different genotype groups.

SNPs Genotype Patients (n) Nausea (%) Vomiting (%) Respiratory depression (%) Pruritus (%)
OPRM1 rs1799971 AA 115 4 (3.48%) 3 (2.61%) 2 (1.74%) 1 (0.87%)
AG 78 2 (2.56%) 1 (1.28%) 1 (1.28%) 1 (1.28%)
GG 32 1 (3.13%) 0 (0) 0 (0) 0 (0)
OPRM1 rs563649 AA 104 3 (2.88%) 3 (2.88%) 2 (1.92%) 2 (1.92%)
AG 78 2 (2.56%) 1 (1.28%) 0 (0) 0 (0)
GG 43 2 (4.56%) 0 (0) 1 (2.33%) 0 (0)
OPRM1 rs1323040 CC 124 5 (4.03%) 4 (3.23%) 3 (2.42%) 2 (1.61%)
CT 79 3 (3.80%) 0 (0) 0 (0) 0 (0)
TT 22 0 (0) 0 (0) 0 (0) 0 (0)
ABCB1 rs2032582 GG 109 4 (3.67%) 4 (3.67%) 2 (1.8%) 1 (0.92%)
GT 85 3 (3.53%) 0 (0) 1 (1.18%) 0 (0)
TT 31 0 (0) 0 (0) 0 (0) 1 (3.23%)
ABCB1 rs1045642 CC 120 4 (3.33%) 3 (2.50%) 3 (2.50%) 2 (1.67%)
CT 58 2 (3.45%) 0 (0) 0 (0) 0 (0)
TT 47 1 (2.13%) 1 (2.13%) 0 (0) 0 (0)
ABCB1 rs1128503 CC 131 5 (3.82%) 4 (3.05%) 2 (1.53%) 1 (0.76%)
CT 63 2 (3.17%) 0 (0) 1 (1.59%) 1 (1.59%)
TT 31 0 (0) 0 (0) 0 (0) 0 (0)