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. 2019 Jan 3;39(1):BSR20181380. doi: 10.1042/BSR20181380

Figure 3. The effect of total flavonoids on the expression of IL-6, SOCS3, Ki67 and phosphorylation of STAT3 in ovarian tissues of PCOS rats.

Figure 3

(A) The expression of IL-6, SOCS3, Ki67 and phosphorylation of STAT3 in ovaries of PCOS rats were detected by IHC. (B) The changes of IL-6, SOCS3, p-STAT3 and Ki67 expression in ovaries of PCOS rats after treated with different concentrations of total flavonoids and Metformin. IHC score was determined according to the percentage of positively staining cells; *P<0.05, **P<0.01, ***P<0.001, **** P<0.0001 vs. PCOS.