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. 2019 Jan 11;39(1):BSR20180201. doi: 10.1042/BSR20180201

Figure 1. Angiotensinogen is the substrate of all angiotensin peptides.

Figure 1

ASOs targeting AGT inhibit AGT synthesis, thereby its downstream peptides. Solid arrows: classic components of the renin–angiotensin system. Dashed arrows: newly identified angiotensin peptides after 2000. Abbreviations: AGT, angiotensinogen; ASO, antisense oligonucleotide.