Table 3.

Comparison of baseline characteristics among Japanese patients with coma after cardiac arrest (n = 46), according to favorable and unfavorable outcomes

	Total (n = 46)	Favorable outcome (n = 19)	Unfavorable outcome (n = 27)	P‐value
Age, years	62.0 (48.5–71.3)	51.0 (34.0–68.0)	67.0 (59.0–74.0)	0.016
Sex, male	38 (83)	16 (84)	22 (82)	0.810
BMI	22.2 (18.4–24.2)	22.8 (19.4–24.5)	21.7 (18.4–23.3)	0.292
Initial rhythm of VT/VF	26 (57)	12 (63)	14 (52)	0.446
Time from collapse to ROSC, min	30.5 (18.0–50.0)	24.0 (15.0–41.0)	45.0 (27.0–54.0)	0.018
Witnessed cardiac arrest	43 (94)	19 (100)	24 (89)	0.133
Adrenaline dose at resuscitation, mg	3.0 (0.0–4.0)	1.0 (0.0–4.0)	3.0 (1.0–5.0)	0.072
Provision of defibrillation	25 (54)	11 (58)	14 (52)	0.685
Prehospital ROSC	14 (30)	8 (42)	6 (22)	0.149
In‐hospital cardiac arrest	11 (24)	4 (21)	7 (26)	0.703
Bystander CPR	19 (41)	11 (58)	8 (30)	0.055
Cardiac origin of arrest	32 (70)	15 (79)	17 (63)	0.246
Coronary disease	15 (33)	7 (37)	8 (30)	0.607
CAI
Day 1	5.00 (2.00–12.48)	4.00 (0.00–12.00)	8.00 (2.00–16.00)	0.042
Day 2	4.50 (1.23–9.25)	2.50 (0.10–8.00)	5.00 (1.00–11.00)	0.533
Day 3	3.00 (0.25–8.00)	4.00 (0.90–8.00)	3.00 (0.30–9.00)	0.796
Day 4	2.00 (0.00–5.63)	2.00 (0.90–5.00)	2.00 (0.00–6.00)	0.697
Day 5	1.10 (0.00–4.13)	0.00 (0.00–4.00)	2.00 (0.00–5.00)	0.173
Day 6	0.00 (0.00–3.00)	0.00 (0.00–2.00)	0.00 (0.00–4.00)	0.163
Survival	33 (72)	18 (95)	15 (56)	0.004

Data are shown as median (range) or n (%).

Favorable outcome = cerebral performance category score 1–2; unfavorable outcome = score 3–5.

Catecholamine index (CAI) = hourly doses (μg/kg/min) of dopamine + dobutamine + (adrenaline + noradrenaline) × 100 (μg/kg/min).

CAI of each day was calculated at the highest point of the day.

BMI, body mass index; CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation; VF, ventricular fibrillation; VT, ventricular tachycardia.