Table 4.
Univariate and multivariate logistic regression analyses of neurological outcome among Japanese patients with coma after cardiac arrest (n = 46)
| Lymphocyte count, 100/μL | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | P‐value | Odds ratio | 95% CI | P‐value | ||
| Model 1 | |||||||
| Day 1 | 0.877 | 0.727–1.059 | 0.172 | Lymphocyte count on day 2 | 0.753 | 0.583–0.972 | 0.029 |
| Day 2 | 0.824 | 0.693–0.980 | 0.029 | SOFA score without GCS on day 1 | 0.861 | 0.586–1.265 | 0.447 |
| Day 3 | 0.770 | 0.593–1.000 | 0.050 | Age | 1.075 | 0.986–1.177 | 0.099 |
| Day 4 | 0.432 | 0.200–0.935 | 0.033 | Time from collapse to ROSC (min) | 1.086 | 1.003–1.177 | 0.043 |
| Day 5 | 0.769 | 0.618–0.957 | 0.019 | Model 2 | |||
| Day 6 | 0.683 | 0.510–0.914 | 0.010 | Lymphocyte count on day 3 | 0.679 | 0.470–0.983 | 0.040 |
| SOFA score without GCS on day 1 | 1.224 | 1.011–1.482 | 0.039 | SOFA score without GCS on day 1 | 0.889 | 0.488–1.619 | 0.701 |
| Age | 1.047 | 1.008–1.087 | 0.019 | Age | 1.120 | 0.986–1.271 | 0.081 |
| Time from collapse to ROSC (min) | 1.044 | 1.005–1.084 | 0.025 | Time from collapse to ROSC (min) | 1.084 | 0.982–1.196 | 0.110 |
| Initial rhythm of VT/VF | 0.628 | 0.189–2.085 | 0.447 | Model 3 | |||
| Lymphocyte count on day 4 | 0.400 | 0.160–1.000 | 0.050 | ||||
| SOFA score without GCS on day 1 | 1.383 | 0.647–2.956 | 0.403 | ||||
| Age | 0.987 | 0.898–1.085 | 0.789 | ||||
| Time from collapse to ROSC (min) | 1.053 | 0.955–1.162 | 0.296 | ||||
| Model 4 | |||||||
| Lymphocyte count on day 5 | 0.791 | 0.593–1.055 | 0.111 | ||||
| SOFA score without GCS on day 1 | 0.976 | 0.711–1.340 | 0.881 | ||||
| Age | 1.053 | 0.980–1.119 | 0.169 | ||||
| Time from collapse to ROSC (min) | 1.075 | 0.996–1.159 | 0.062 | ||||
| Model 5 | |||||||
| Lymphocyte count on day 6 | 0.687 | 0.475–0.993 | 0.046 | ||||
| SOFA score without GCS on day 1 | 0.865 | 0.618–1.209 | 0.395 | ||||
| Age | 1.063 | 0.996–1.135 | 0.066 | ||||
| Time from collapse to ROSC (min) | 1.026 | 0.972–1.084 | 0.349 | ||||
Sequential organ failure assessment (SOFA) score without Glasgow Coma Scale (GCS) on day 1 was measured as the worst data within the first 24 h, excluding GCS score.
Model 1 included lymphocyte count on day 2, SOFA score on day 1, age and time from collapse to return of spontaneous circulation (ROSC), for which the P‐values were < 0.1. Model 2 included lymphocyte count on day 3, SOFA score on day 1, age and time from collapse to ROSC, for which the P‐values were < 0.1. Model 3 included lymphocyte count on day 4, SOFA score on day 1, age and time from collapse to ROSC, for which the P‐values were < 0.1. Model 4 included lymphocyte count on day 5, SOFA score on day 1, age and time from collapse to ROSC, for which the P‐values were < 0.1. Model 5 included lymphocyte count on day 6, SOFA score on day 1, age and time from collapse to ROSC, for which the P‐values were < 0.1.
CI, confidence interval.