Figure 4.

Angelica polysaccharide (AP) activated the Nrf2/HO-1 pathway while inhibited the NF-κB pathway in HaCaT cells. HaCaT cells were stimulated with 10 μg/mL LPS or 100 μg/mL AP plus 10 μg/mL LPS. Non-treated cells acted as control. Then, expressions of key kinases in (a) the Nrf2/HO-1 pathway and (b) the NF-κB pathway were evaluated by western blot analysis. Data were presented as the mean ± SEM of three independent experiments. CTRL: control; t-: total; p-: phospho-.

*P < 0.05; **P < 0.01; ***P < 0.001.