Table 4.

Blood metabolites correlated with blood lipids and serum Hp levels in non-DM subjects

Metabolites	Total cholesterol	Triglycerides	HDL-C	LDL-C	Serum Hp	Carotid IMT
Lyso-phosphatidylcholines (μM)
LysoPC a C16:0	− 494.124 ± 89.651	39.362 ± 16.748	133.887 ± 36.720	310.854 ± 52.472	− 5.264 ± 2.417	25.137 ± 34.301
	< 0.0001	0.0207	0.0004	<0.0001	0.0317	0.4653
LysoPC a C17:0	− 3.953 ± 1.356	0.401 ± 0.253	1.140 ± 0.555	2.706 ± 0.793	− 0.088 ± 0.037	− 0.303 ± 0.519
	0.0043	0.1160	0.0425	0.0009	0.0183	0.5606
LysoPC a C18:2	52.100 ± 26.226	− 2.782 ± 4.899	− 0.547 ± 10.742	− 28.897 ± 15.350	− 1.675 ± 0.707	− 5.400 ± 10.034
	0.0496	0.5714	0.9595	0.0626	0.0197	0.5916
LysoPC a C24:0	− 1.237 ± 0.515	0.239 ± 0.096	0.724 ± 0.211	0.648 ± 0.301	− 0.031 ± 0.014	0.191 ± 0.197
	0.0181	0.0145	0.0009	0.0339	0.0302	0.3344
Phosphatidylcholines (μM)
PC ae C32:2	0.007 ± 0.463	0.029 ± 0.087	0.478 ± 0.190	0.114 ± 0.271	− 0.026 ± 0.012	− 0.229 ± 0.177
	0.9886	0.7380	0.0133	0.6752	0.0390	0.2000
PC ae C34:0	− 0.158 ± 0.737	0.284 ± 0.138	0.666 ± 0.302	0.075 ± 0.431	− 0.041 ± 0.020	− 0.080 ± 0.282
	0.8312	0.0418	0.0295	0.8621	0.0441	0.7761
PC ae C34:3	15.585 ± 3.858	− 1.788 ± 0.721	1.492 ± 1.580	− 6.850 ± 2.258	− 0.230 ± 0.104	− 2.803 ± 1.476
	0.0001	0.0148	0.3473	0.0031	0.0292	0.0605
PC ae C36:2	29.048 ± 6.159	− 0.149 ± 1.151	− 2.674 ± 2.523	− 15.795 ± 3.605	− 0.338 ± 0.166	− 2.884 ± 2.356
	< 0.0001	0.8969	0.2915	< 0.0001	0.0446	0.2238
PC ae C40:1	2.153 ± 0.872	0.357 ± 0.163	0.862 ± 0.357	− 0.748 ± 0.510	− 0.074 ± 0.024	− 0.253 ± 0.334
	0.0152	0.0306	0.0176	0.1456	0.0020	0.4491
Amino acids (μM)
Gln	865.339 ± 430.321	− 124.218 ± 80.390	− 303.854 ± 176.254	− 428.871 ± 251.864	− 32.233 ± 11.602	− 127.624 ± 164.646
	0.0469	0.1254	0.0877	0.0916	0.0065	0.4400

Multiple linear regression analysis was used to perform the analysis after adjusting for age, sex and body mass index with total cholesterol, triglycerides, HDL-C, LDL-C, serum Hp level tertiles and carotid IMT as independent variables. β ± SE and P values are shown in table

Non-DM non-diabetes mellitus, Hp haptoglobin, Gln Glutamine, HDL-C high-density lipoprotein-cholesterol, LDL-C low-density lipoprotein-cholesterol, IMT intima-media thickness

P values < 0.05 are shown in italic