Table 3.

IC₅₀ of each parent, mutant derivative, and complementation derivative strain and the percent differences of tolerance relative to the parent strain

Treatment		SD100	SD100 Δslr2131	SD100 Δslr2131 pacrB	SD100 Δsll0180	SD100 Δsll0180 pSacrA
Amp	IC50	955.2 ± 256 μg/mL	1280 ± 230 μg/mL (ns)	891 ± 117 μg/mL (ns)	598 ± 296 μg/mL	577.0 ± 23.2 μg/mL
	% diff from SD100	0%	34%	−6.7%	37%	39%
Cm	IC50	2.290 ± 0.401 μg/mL	0.586 ± 0.142 μg/mL	2.124 ± 1.004 μg/mL (ns)	1.442 ± 0.206 μg/mL	4.73 ± 1.47 μg/mL
	% diff from SD100	0%	−74%	−7.2%	−37%	106%
Ery	IC50	0.358 ± 0.081 μg/mL	0.054 ± 0.002 μg/mL	0.103 ± 0.019 μg/mL	0.172 ± 0.1 μg/mL	0.144 ± .028 μg/mL
	% diff from SD100	0%	−85%	−71%	−52%	−60%
Treatment		SD277	SD277 Δslr2131	SD277 Δslr2131 pacrB	SD277 Δsll0180	SD277 Δsll0180 pSacrA
Amp	IC50	1570 ± 170 μg/mL	1001 ± 120 μg/mL	980.3 ± 37 μg/mL	450 ± 119 μg/mL	286.6 ± 113.8 μg/mL
	% diff from SD277	0%	−36%	−38%	−71%	−82%
Cm	IC50	4.749 ± 1.043 μg/mL	1.873 ± 0.354 μg/mL	3.305 ± 1.100 μg/mL (ns)	1.085 ± 0.589 μg/mL	3.486 ± 1.027 μg/mL (ns)
	% diff from SD277	0%	−61%	−30%	−77%	−27%
Ery	IC50	0.427 ± 0.249 μg/mL	0.171 ± 0.044 μg/mL	0.095 ± 0.007 μg/mL	0.034 ± 0.007 μg/mL	0.075 ± 0.014 μg/mL
	% diff from SD277	0%	−60%	−78%	−92%	−82%

The basis for the comparison in this table were the parent strains, either SD100 or SD277, featured in the third column. The data values for each derivative strain are significantly different from the parent strain unless otherwise noted with “(ns)”