Table 1.
Demographic and spirometric data from patients included in the study
| All COPD patients n = 551 |
AAT deficiency n = 40 |
Pi*ZZ n = 11 |
p-value | |
|---|---|---|---|---|
| Male: female | 283:268 | 21:19 | 4:7 | – |
| Age (mean ± SD) | 65.2 ± 14.0 | 63.2 ± 10.2 | 60.0 ± 7.3 | 0.19 |
| Smoking (pack-years) | 46.5 ± 41.2 | 34.7 ± 36.9 | 4.1 ± 11.2 | 0.02 |
| FEV1 (% predicted) | 50.2 ± 20.6 | 49.1 ± 20.4 | 37.7 ± 7.9 | 0.22 |
| FVC (% predicted) | 76.3 ± 22.3 | 79.4 ± 19.2 | 78.8 ± 21.4 | 0.75 |
| FEV1/FVC (%) | 50.7 ± 13.6 | 49.0 ± 13.6 | 41.9 ± 14.6 | 0.18 |
The difference among the three groups was analyzed by ANOVA followed by Turkey’s multiple comparison test
COPD chronic obstructive pulmonary disease, SD standard deviation, FEV1 forced expiratory volume at first second, FVC forced vital capacity