Table 3.

Demographic characteristics and clinical signs of children according to the biofilm production

Characteristics and clinical signs	Biofilm production by H. influenzae	p*	Biofilm production by S. pneumoniae	p*
Day-care center	47/72 (65.3)	0.66	42/63 (66.7)	0.99
Recurrent acute otitis media	22/33 (66.7)	0.77	19/29 (65.5)	0.87
Conjunctivitis	59/97 (60.8)	0.27	42/66 (63.6)	0.52
Otalgia	96/145 (66.2)	0.26	105/156 (67.3)	0.68
Temperature > 38.5 °C	42/56 (75.0)	0.047	45/71 (63.4)	0.46
Fever + otalgia	50/67 (74.6)	0.025	58/86 (67.4)	0.87
Antibiotics 3 months before enrollment	53/87 (60.9)	0.34	55/82 (67.1)	0.95

*p comparing biofilm strain producers and non-producers