Table 1.
Statistical analysis of data presented in Fig. 2. Post hoc results are only shown for tests which reached statistical significance (P < 0.05)
| DF | eta squared Cohen’s d | F (DFn, DFd) t | P value | |
|---|---|---|---|---|
| GPER (two-way) | ||||
| Interaction | 7 | 8.56 | F (7, 77) = 4.08 | P = 0.0007 |
| Tissue | 7 | 67.1 | F (7, 77) = 32.0 | P < 0.0001 |
| Sex | 1 | 0.0137 | F (1, 77) = 0.0459 | P = 0.8310 |
| >Kidney F vs. M | 77 | 1.07 | t = 2.96 | P = 0.0327 |
| >Gonads F vs. M | 77 | − 4.75 | t = 3.72 | P = 0.0030 |
| ESR1 (two-way) | ||||
| Interaction | 7 | 20.2 | F (7, 79) = 19.2 | P < 0.0001 |
| Tissue | 7 | 65.5 | F (7, 79) = 62.3 | P < 0.0001 |
| Sex | 1 | 1.91 | F (1, 79) = 12.7 | P = 0.0006 |
| >Kidney F vs. M | 79 | − 3.08 | t = 11.8 | P < 0.0001 |
| ESR2 (two-way) | ||||
| Interaction | 7 | 37.4 | F (7, 78) = 18.6 | P < 0.0001 |
| Tissue | 7 | 34.8 | F (7, 78) = 17.3 | P < 0.0001 |
| Sex | 1 | 5.07 | F (1, 78) = 17.6 | P < 0.0001 |
| >Gonads F vs. M | 78 | 3.57 | t = 12.2 | P = 0.0030 |
| CYP19A1 (two-way) | ||||
| Interaction | 7 | 26.3 | F (7, 78) = 7.06 | P < 0.0001 |
| Tissue | 7 | 28.4 | F (7, 78) = 7.62 | P < 0.0001 |
| Sex | 1 | 3.67 | F (1, 78) = 6.89 | P = 0.0104 |
| >Gonads F vs. M | 78 | 2.19 | t = 12.2 | P = 0.0030 |