Table 4.

Statistical analysis of data presented in Fig. 5. Post hoc results are only shown for tests which reached statistical significance (P < 0.05)

	DF	eta squared Cohen’s d	F (DFn, DFd) t	P value
Gonads (two-way)
Interaction	3	17.8	F (3, 38) = 5.33	P = 0.0037
Sex	1	12.2	F (1, 38) = 11.0	P = 0.0020
>CYP19A1: F vs. M	38	2.19	t = 4.95	P < 0.0001
gene	3	25.4	F (3, 38) = 7.62	P = 0.0004
>F: GPER vs. ESR1	38	− 6.01	t = 3.82	P = 0.0029
>F: GPER vs. CYP19A1	38	− 2.20	t = 4.97	P < 0.0001
>F: ESR2 vs. CYP19A1	38	− 1.44	t = 3.75	P = 0.0035
Mammary (one-way)
Gene	3	64.5	F (3, 20) = 12.12	P < 0.0001
>F: GPER vs. ESR1	20	− 2.23	t = 4.13	P = 0.0031
>M: GPER vs. ESR1	20	2.98	t = 5.163	P = 0.0003
>M: GPER vs. ESR2	20	3.00	t = 5.18	P = 0.0003
Uterus (one-way)
Gene	3	92.2	F (3, 8) = 31.7	P < 0.0001
>F: GPER vs. ESR1	8	− 6.66	t = 8.01	P = 0.0003
>M: GPER vs. ESR1	8	6.80	t = 8.14	P = 0.0002
>M: GPER vs. ESR2	8	4.94	t = 7.70	P = 0.0003