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. 2019 Jan 11;20:9. doi: 10.1186/s12881-018-0739-x

Fig. 1.

Fig. 1

Effect specification for various interaction scenarios. βGE and βGTE are interaction effect parameters for gene-environment and gene-time-environment interactions respectively. Genetic (G) factor coded as 0, 1, and 2 for the number of minor alleles. Environment (E) factor coded as 1 or 0 for presence or absence of the environmental exposure. The tables in each panel present the interaction effect θijk associated with each combination of the genetic (G) and environmental (E) factors