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. 2019 Jan 11;16:4. doi: 10.1186/s12986-018-0327-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Micro-CT of osteotomy site in tibia revealed only minor effects of baicalein. The parameters measured in tibiae were bone volume/total volume (BV/TV, a), total BMD (b), cortical BMD (c), and callus BMD (d), as well as callus volume (e) and total volume (f). For callus BMD (d), ovariectomy led to reduced values, while callus volume (e) was significantly reduced at the highest baicalein concentration. ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05 (NON-OVX n = 9, OVX n = 9, C1 n = 9, C2 n = 9, C3 n = 10)