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. 2019 Jan 11;10:12. doi: 10.1186/s13287-018-1115-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Establishment of rat tibial distraction osteogenesis model. a Schematic diagram illustrating the timeline of the rat tibial distraction osteogenesis procedures. b Representative photograph after application of external fixation. c Photograph at 4 weeks after consolidation. d In vivo imaging of Exos or EPCs stained with DiR at 2 weeks after injection. EPCs endothelial progenitor cells, Exo exosomes secreted by EPCs