Table 3.
Results of 2-Way ANOVA in Plasma Samples
|
miR |
P |
Fold Change |
|
|
Cohort 1 |
Cohort 2 |
||
| hsa-miR-4667-5p | 4.1E-05 | 2.55 | 1.72 |
| hsa-miR-99b-3p | 4.8E-05 | 3.17 | 2.02 |
| hsa-miR-637 | 5.1E-05 | 2.53 | 2.37 |
| hsa-miR-4490 | 5.7E-05 | 4.19 | 1.88 |
| hsa-miR-1253 | 6.0E-05 | 3.58 | 1.93 |
| hsa-miR-3190-3p | 3.1E-04 | 3.08 | 1.69 |
| hsa-miR-3173-3p | 0.001 | 3.68 | 1.98 |
| hsa-miR-608 | 0.001 | 3.07 | 1.89 |
| hsa-miR-4725-3p | 0.002 | 4.69 | 1.57 |
| hsa-miR-4448 | 0.002 | 2.08 | 1.96 |
| hsa-miR-323b-5p | 0.002 | 4.88 | 1.72 |
| hsa-miR-4538 | 0.003 | 3.24 | 2.09 |
| hsa-miR-3913-3p | 0.003 | 1.70 | 1.67 |
| hsa-miR-3159 | 0.003 | 2.31 | 1.62 |
| hsa-miR-4663 | 0.003 | 2.39 | 2.19 |
| hsa-miR-4767 | 0.003 | 1.81 | 1.67 |
| hsa-miR-4724-5p | 0.003 | 2.46 | 1.54 |
| hsa-miR-1306-5p | 0.003 | 1.34 | 2.55 |
| hsa-miR-181b-3p | 0.004 | 1.92 | 1.80 |
| hsa-miR-433-3p | 0.004 | 3.02 | 1.56 |
ANOVA P values are reported for disease state (glaucoma/XFS versus cataract controls). These P values all met threshold significance after adjustment for false discovery rate using the Benjamini-Hochberg method. Fold change is 2-ΔCT of glaucoma versus cataracts for each cohort.