Table 4.

Logistic Regression Statistics for Cohort 2 Data (Japan)

miRNA	Odds Ratio	95% CI	P Value
Univariate Analysis
hsa-miR-4667-5p	4.14	1.5–11.4	0.006
hsa-miR-99b-3p	4.13	1.5–11.3	0.006
hsa-miR-637	8.64	1.8–42.2	0.008
hsa-miR-4490	3.16	1.4–7.3	0.008
hsa-miR-1253	3.41	1.4–8.0	0.005
hsa-miR-3190-3p	2.93	1.2–7.1	0.02
hsa-miR-3173-3p	2.56	1.1–6.0	0.03
hsa-miR-608	2.84	1.3–6.4	0.01
hsa-miR-4725-3p	2.25	1.0–5.1	0.05
hsa-miR-4448	2.95	1.3–6.9	0.01
hsa-miR-323b-5p	2.30	1.1–4.8	0.03
hsa-miR-4538	2.55	1.0–6.6	0.06
hsa-miR-3913-3p	2.90	1.2–6.8	0.01
hsa-miR-3159	2.26	1.1–4.9	0.03
hsa-miR-4663	9.80	1.9–50.5	0.006
hsa-miR-4767	4.61	1.4–15.5	0.01
hsa-miR-4724-5p	1.91	1.0–3.8	0.07
hsa-miR-1306-5p	2.40	1.2–4.8	0.01
hsa-miR-181b-3p	3.47	1.2–10.2	0.02
hsa-miR-433-3p	1.82	1.0–3.6	0.09
Multivariate Analysis*
hsa-miR-637	2031.9	2.9–1 417 266	0.02
hsa-miR-1306-5p	24.5	1.9–312	0.01
hsa-miR-3159	0.002	5.1 × 10−06–0.9	0.05

^*Three of these retained significance in a multivariate analysis, suggesting that their combination may improve disease classification or detection.