Table 3.

Antihypertensive drugs in pregnancy

1st choice	Alternative first-line	Second-line	Third-line	Contraindicated in pregnancy
Labetalol	Nifedipine (MR)	Methyldopa	Doxazosin	ACE inhibitors (safe when breastfeeding*)
		Amlodipine	Hydralazine	Angiotensin II receptor antagonists Spironolactone
			Selective β-blockers

*Avoid in acute kidney injury. Enalapril and captopril are the preferred agents, as safety data are limited for other drugs in this class.

ACE = angiotensin-converting enzyme; MR = modified release