Table 2. Imputed gene expression levels associated† with birth weight, childhood obesity and childhood BMI.
| Gene ID | Gene Symbol | MetaXcan | Gene ID | Gene Symbol | MetaXcan | ||
|---|---|---|---|---|---|---|---|
| Effect Size | P value | Effect Size | P value | ||||
| Birth Weight | Childhood Obesity | ||||||
| ENSG00000181885 | CLDN7 | 0.0754 | 6.78E-15 | ENSG00000138031 | ADCY3 | 0.4200 | 2.62E-10 |
| ENSG00000164532 | TBX20 | -0.0247 | 8.38E-09 | ENSG00000115137 | DNAJC27 | 0.4494 | 1.69E-05 |
| ENSG00000123104 | ITPR2 | -0.0519 | 7.80E-07 | ENSG00000162623 | TYW3 | -1.319 | 8.34E-04 |
| ENSG00000144401 | METTL21A | 0.0396 | 1.37E-06 | ||||
| ENSG00000114127 | XRN1 | 0.0688 | 1.40E-06 | Childhood BMI | |||
| ENSG00000170606 | HSPA4 | -0.0773 | 8.31E-06 | ENSG00000138031 | ADCY3 | 0.1755 | 6.00E-17 |
| ENSG00000107679 | PLEKHA1 | -0.0253 | 9.22E-06 | ENSG00000135451 | TROAP | -0.5336 | 2.78E-10 |
| ENSG00000153214 | TMEM87B | 0.0646 | 9.82E-06 | ENSG00000134287 | ARF3 | -0.1280 | 3.91E-08 |
| ENSG00000092036 | HAUS4 | 0.0539 | 1.22E-05 | ENSG00000115137 | DNAJC27 | 0.1537 | 1.11E-06 |
| ENSG00000144891 | AGTR1 | 0.1049 | 1.32E-05 | ENSG00000001617 | SEMA3F | 0.2385 | 1.63E-04 |
| ENSG00000090621 | PABPC4 | 0.0483 | 1.68E-05 | ENSG00000138615 | CILP | -0.1585 | 2.32E-04 |
| ENSG00000128891 | C15orf57 | -0.0214 | 3.07E-05 | ||||
| ENSG00000146374 | RSPO3 | 0.0576 | 3.31E-05 | ||||
| ENSG00000006282 | SPATA20 | -0.0158 | 3.57E-05 | ||||
| ENSG00000141295 | SCRN2 | 0.0228 | 4.50E-05 | ||||
| ENSG00000124467 | PSG8 | 0.0343 | 7.29E-05 | ||||
| ENSG00000159111 | MRPL10 | -0.0655 | 7.35E-05 | ||||
| ENSG00000166033 | HTRA1 | -0.0289 | 8.24E-05 | ||||
| ENSG00000172243 | CLEC7A | -0.0617 | 8.97E-05 | ||||
†Only MetaXcan results that passed Bonferroni correction are shown. The Effect Size refers to the change of gene expression associated with phenotype trait (ie, birth weight, childhood obesity, and childhood BMI) inferred by MetaXcan. Positive effect size indicates the gene expression level is positively correlated with the phenotypic trait; and negative effect size indicates negative correlation.