Table 4. Overlap of GWAS signals for birth weight GWAS and childhood obesity GWAS.
GWAS P value threshold | Overlap OR | Number of overlap SNPs | N of overlap SNPs consistent risk allele | % SNPs with consistent risk allele | p-value of risk allele consistent |
---|---|---|---|---|---|
1.0E-03 | 1.55 | 36 | 33 | 91 | 3.52E-07 |
1.0E-02 | 1.77 | 1062 | 713 | 67 | 7.07E-29 |
1.0E-01 | 1.12 | 32613 | 20336 | 62 | 1.53E-322 |
P value threshold; GWAS p value threshold applied to both birth weight GWAS and childhood obesity GWAS. Consistent direction allele; the SNPs where the same allele association with higher birth weight and higher child obesity.